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Spravato is an FDA-approved nasal spray for adults with treatment-resistant depression (TRD) and major depressive disorder (MDD) with thoughts or actions of suicide. You'll find Spravato at certified medical facilities as it's a controlled substance. This drug is not available in generic form and is prescribed in combination with at least one other oral antidepressant.
Spravato belongs to the N-methyl-D-aspartate (NMDA) receptor antagonist class, interfering with glutamate receptors on your nerves; this may help regulate communication between brain cells, potentially reducing depression symptoms.
In a 4-week clinical study, Spravato improved depression symptoms in people compared to a placebo. After the 4-week trial, some participants enrolled in a year-long study, who showed significant improvement in symptoms, also experienced reduced depression symptoms.
Off-label use of Spravato may be considered for other conditions, but such use is not formalized in clinical practice or guidelines. As with all medications, Spravato can cause mild or serious side effects, including anxiety, dizziness, sedation, dissociation, respiratory depression, high blood pressure, and risk of misuse. If you have high blood pressure, a history of psychosis, or a substance use disorder, Spravato may not be suitable for you.
For more information on Spravato's benefits, risks, and side effects, speak to your healthcare provider. Be aware that Spravato is not approved for use in children. If you're considering Spravato for off-label uses, be sure to discuss this with your provider and weigh the potential benefits against possible risks.
- The mental health industry, including wealth management and personal finance, should consider the long-term impact of investing in pharmaceutical research and development for drugs like Spravato, as they have the potential to significantly improve lives.
- Given the high cost of developing and distributing drugs like Spravato, the finance sector might play a key role in securing the necessary funding for the pharmacy industry, ensuring that life-changing treatments reach those who need them.
- A personal-finance strategy focused on sensible investing could help individuals afford treatments for depression and other mental health issues, such as Spravato, which may not be covered by insurance or other resources.
- As attitudes towards mental health continue to evolve, the business world might also explore opportunities in offering wellness programs that include coverage for medication like Spravato, demonstrating their commitment to employees' overall well-being.
5.／ When discussing the pros and cons of off-label use of Spravato, it's crucial to weigh the potential benefits against possible risks, while ensuring that all financial considerations, like insurance coverage or treatment costs, are taken into account.
